Overview of the Glimma package
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چکیده
Glimma is a Bioconductor package for interactive visualization of the results from a differential expression analysis of RNA-sequencing data. This functionality is intended to enhance reporting capabilities so that results can be explored more easily by end-users. Glimma (which loosely stands for Interactive Graphics from the limma package) extends some of the popular plotting capabilities in limma [1] such as multidimensional scaling (MDS) plots, that can be useful for visualising relationships between samples, and mean-difference plots (MD plots) for summarising results from comparisons of interest. The choice of displays and layouts used was inspired by visualisations in the Degust software [2]. The Glimma package is designed to handle RNA-seq differential expression results from the limma, edgeR [3] and DESeq2 [4] packages. Figure 1 below provides an overview of this functionality.
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تاریخ انتشار 2016